Posts
News, announcements, blog posts, and paper-like investigations from Dalea.
But can it run Doom?
Your LIMS might be powerful. It might even be adaptable. But can it run Doom? This week’s paper is about adaptability, scientific iteration, and why we built a completely unnecessary first-person shooter inside Dalea to test a much more useful idea: whether scientists can shape their software around the work they are actually doing.
The Auditman Cometh
Every child's boogeyman lives under the bed. Biopharma's lives in the gap between doing the work and proving you did it, and he arrives on a schedule. Three-quarters of FDA rejection letters cite quality and manufacturing problems, the same Form 483 findings recur year after year, and food now has twenty-four hours to produce lot-level traceability. Weekly Papers #5 on why audits are almost never lost on the science, and what it would mean for compliance to be a property of the system, not a project.
Someone else must have run this experiment before...
They almost certainly have. The problem is that what they learned is published as guidance, while the setup itself stays trapped in their lab. Weekly Papers #4 on why scientific structure rarely travels.
Dalea is now an official community connector for Claude.
The foundation of Dalea is build on many philosophies, one essential part is: a research platform shouldn't have a human version and an AI version. It should b...
Biology has no compiler
Agentic AI arrived in the lab this year on the strength of what it did for software. But what makes coding agents work, a compiler and a test suite that tell you deterministically whether the work is right, has no equivalent in biological research. Weekly Papers #3 on why the answer to trustworthy AI in life science isn't a bigger agent, more agents, or more skills, but a deterministic substrate that audits and traces every action, whether human, AI, or programmatic, in a language built for science.
The Same Algorithm, Half the Patients
Two health databases. Same year, same country, same conditions - and on average every condition looked 12% more prevalent in one than the other. Then someone standardised what counted as an "inpatient visit," and the gap fell to 1%. Weekly Papers #2 on why checking another group's work means rebuilding their data model, why almost everyone rebuilds it from scratch, and what it would mean to install it instead.
An ELN isn't just an ELN
When we share lab work, we argue about export formats — PDF, CSV, a folder of attachments. But that's the wrong question. Before asking how to export the work, ask what the work actually is: a protocol, a data model, code, queries, and charts that depend on one another. Weekly Papers #1 on why the natural unit of scientific sharing is the package, not the page.